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Outcomes of Other Prescription drugs on VIAGRA Sildenafil metabolism is principally mediated by CYP3A4 (major route) and CYP2C9 (slight route). For that reason, inhibitors of these isoenzymes may perhaps cut down sildenafil clearance and inducers of these isoenzymes may possibly maximize sildenafil clearance.The principal indicator of sildenafil is… Read More